Disease intelligence is central to the region’s effort to eliminate malaria. As the malaria patterns extend across national borders, it is important that countries extend their surveillance activities to include information about transmission beyond their own borders. E8 countries have committed to sharing of disease transmission patterns and harmonization of surveillance systems in order to develop regional-level analyses on malaria transmission and outbreak risks. A regional surveillance platform capable of assessing expands the data available to countries and the value of the data, using regional patterns to assess cross-border trends, outbreak risks, and to enhance data for decision-making.